MORPHOGENESIS OF FUNGIFORM PAPILLAE IN DEVELOPING MINIATURE PIGS

Morphogenesis of fungiform papillae in developing miniature pigs

Objective: Fungiform papillae contain taste buds and play a critical role in mastication and the gustatory system.In this study, we report a series of sequential observations of organogenesis of fungiform papillae in miniature pigs, as well as changes in the expression of BMP2, BMP4, Wnt5a, Sox2, and Notch1 signaling pathway components.Design: In t

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Trial registration as a safeguard against outcome reporting bias and spin? A case study of randomized controlled trials of acupuncture.

BACKGROUND AND OBJECTIVE:Trial registration is widely endorsed as it is considered not only to enhance transparency and quality of reporting but also to help safeguard against outcome reporting bias and probably spin, known as specific reporting that could distort the interpretation of results thus mislead readers.We planned to investigate the curr

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Connexin 43 regulates intercellular mitochondrial transfer from human mesenchymal stromal cells to chondrocytes

Abstract Background The phenomenon of intercellular mitochondrial transfer from mesenchymal stromal cells (MSCs) has shown promise for improving tissue healing after injury and has potential for treating degenerative diseases like osteoarthritis (OA).Recently MSC to chondrocyte mitochondrial transfer has been documented, but the mechanism of transf

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